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Pediatric diabetes medications

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Real-world data support early insulin pump initiation in children

Starting children on an insulin pump within 6 months of type 1 diabetes diagnosis is associated with improved outcomes relative to delaying for 2 or 3 years, shows an analysis of data from the DPV registry.

medwireNews top story

Family conflict key factor in poor glycemic control among young insulin users

Factors associated with poor glycemic control in children with type 1 diabetes generally vary according to the insulin regimen used, but family conflict over diabetes management universally impacts all insulin users, US researchers report.

medwireNews top story

Ellipse trial: Liraglutide expands treatment options for pediatric type 2 diabetes

The Ellipse investigators report improved glycemic control at the price of early and mostly mild gastrointestinal events in children and adolescents with type 2 diabetes.

Interactive patient case study

Hypoglycemia and technology

This 15-minute case presents the identification of problematic hypoglycemia and the appropriate use and monitoring of different technologies in the context of reducing the occurrence and risk of hypoglycemia.

Get more on: Hypoglycemia | Devices and technology | Pediatric diabetes

medwireNews editor's pick

Insulin manipulation strongly linked to psychiatric comorbidity

Insulin manipulation, the practice of deliberately under- or overdosing insulin, is strongly associated with psychiatric comorbidity in children and young adults with type 1 diabetes, Austrian research shows.

medwireNews@ADA2018

RISE: Early insulin does not slow beta cell decline in youth with type 2 diabetes

The RISE trial investigators have found that increased insulin resistance and hyperresponsive beta cells may explain the rapid progression of type 2 diabetes in children.

medwireNews editor's pick

Reassuring long-term data for sulfonylurea in neonatal diabetes

Sulfonylurea treatment is durably effective with a low rate of side effects in patients with permanent neonatal diabetes caused by mutations in the KCNJ11 gene, a study in The Lancet Diabetes & Endocrinology shows.

medwireNews editor's pick

Insulin, metformin remain most used treatments for type 2 diabetes in youths

The majority of adolescents and young adults with type 2 diabetes are still being treated with metformin and/or insulin, despite a growing number of medications being available for adults, US study data show.

Journal article

Glycemic impact of non-nutritive sweeteners: A systematic review and meta-analysis of randomized controlled trials

A systematic review and meta-analysis of randomized controlled trials was conducted to quantitatively synthesize existing scientific evidence on the glycemic impact of non-nutritive sweeteners [read more].
Nichol AD, Holle MJ, An R. Eur J Clin Nutr 2018. doi: 10.1038/s41430-018-0170-6

Get more on: Type 2 diabetes | Glycemic control | Diet and nutritional management

View from the clinic

Managing patient expectations for glucose management via a device

As the utility and availability of devices surges, so too do patient expectations. Advisory Board member Katharine Barnard provides key consultation questions to help determine your patients’ greatest needs and obstacles [read more].

Get more on: Devices and technology | Psychosocial care | Type 1 diabetes | Type 2 diabetes

medwireNews

23-10-2023 | Type 1 diabetes | News

Teplizumab may PROTECT β-cell function in youth with newly diagnosed type 1 diabetes

Early treatment with the anti-CD3 monoclonal antibody teplizumab may help to preserve β-cell function in children and adolescents with newly diagnosed type 1 diabetes, results of the phase 3 PROTECT study show.

03-02-2023 | Empagliflozin | News

DINAMO: Empagliflozin shows promise for young people with type 2 diabetes

Empagliflozin, but not linagliptin, provides “clinically relevant” improvements in glycemic control versus placebo in children and adolescents with type 2 diabetes, report the DINAMO investigators.

09-01-2023 | Semaglutide | News

FDA approves high-dose semaglutide for adolescents with obesity

Read more about this decision here

Themed collections

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07-06-2017 | Psychosocial care | Themed collection | Collection

Psychosocial care in diabetes

This content collection summarizes recent publications dealing with various aspects of psychosocial care in patients with type 1 and type 2 diabetes.

This collection has been developed on behalf of Diabetes UK

Journal articles and book chapters

Child with insulin pump (symbolic image with model)

20-07-2018 | Insulin pumps | Article

Optimizing a hybrid closed loop system in type 1 diabetes: A case report

The authors present the optimization of a hybrid closed-loop insulin pump system in an 11-year-old female with 7 years of type 1 diabetes.

Petrovski G et al. Diabetes Ther 2018. doi: 10.1007/s13300-018-0473-6

27-06-2018 | Metformin | Article

Metformin monotherapy in children and adolescents with type 2 diabetes mellitus in Japan

Matsuura N et al. Diabetol Int 2018. doi: 10.1007/s13340-018-0361-3

26-06-2018 | Devices and technology | Review | Article

Technology in the management of type 1 diabetes mellitus: Current status and future prospects

Tauschmann M Hovorka R. Nat Rev Rheumatol 2018. doi: 10.1038/s41574-018-0044-y

Guidelines

Guidelines

A convenient single access point, providing diabetes professionals with links to a comprehensive set of clinical practice guidelines from a wide range of relevant organizations.

Downloadable slides

Slides

Downloadable PowerPoint slide sets containing a variety of high-quality images and illustrations from Springer Nature’s library of published figures.

In practice

Practice tips

Practical information, guidance, and helpful resources for diabetes healthcare providers. Comprised of practical approaches, case studies, and more.

Themed collections

Themed collections

Compendia of selected, recently published, free full-text journal and book content from Springer Nature and other publishers on a particular topic within diabetes management, as recommended by our Editorial Board.

Independent Medical Education

Independent Medical Education

Educational programs building upon the most current research and professional practice recommendations, with the aim of enabling more efficient diagnosis, optimizing treatment, and improving patient outcomes.