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Pediatric diabetes

Highlights

CGM

17-06-2020 | Continuous glucose monitoring | Highlight | News

Variable CGM benefits in high-risk subgroups

Continuous glucose monitoring is well accepted and reduces time in hypoglycemia among older individuals with type 1 diabetes, report researchers in JAMA.

Motion blur child hospital emergency

19-05-2020 | Children | Highlight | News

DKA prevalence with newly diagnosed pediatric type 1 diabetes remains high

A major study of children from three continents suggests that diabetic ketoacidosis remains unacceptably high among those newly identified with type 1 diabetes and shows few signs of improving.

Close-up of microscope

16-03-2020 | Pathophysiology | Highlight | News

Type 1 diabetes endotypes firmed up

Researchers provide further evidence to support two distinct type 1 diabetes endotypes characterized by a more or less aggressive autoimmune response and a younger or older age at onset.

Overweight boy in a tight shirt

14-02-2020 | Pathogenesis | Highlight | News

Excess weight may hasten type 1 diabetes progression in lower-risk children

A high BMI may contribute to the risk for progressing from single to multiple islet autoantibodies, especially in children who would otherwise be at relatively low risk, show findings from TrialNet.

Hospital emergency sign

03-10-2019 | Ketoacidosis | Highlight | News

Protocol with point-of-care testing improves speed, accuracy of DKA diagnosis

Implementing a nursing protocol that includes point-of-care testing at triage reduces the time to diabetic ketoacidosis diagnosis and the number of unnecessary intravenous placements in the pediatric emergency department, say researchers.

Mother and child with diabetes

28-05-2019 | Children | Highlight | News

Maternal education has major impact on glycemic control in children

Researchers report that women’s educational attainment is strongly associated with the glycated hemoglobin levels of their children with type 1 diabetes.

Family fighting

10-05-2019 | Psychosocial care | Highlight | News

Family conflict key factor in poor glycemic control among young insulin users

Factors associated with poor glycemic control in children with type 1 diabetes generally vary according to the insulin regimen used, but family conflict over diabetes management universally impacts all insulin users, US researchers report.

Injection pens

29-04-2019 | Liraglutide (T2DM) | Highlight | News

Ellipse trial: Liraglutide expands treatment options for pediatric type 2 diabetes

The Ellipse investigators report improved glycemic control at the price of early and mostly mild gastrointestinal events in children and adolescents with type 2 diabetes.

Child with diabetes (symbolic image with model)

04-04-2019 | Insulin pumps | Highlight | News

Randomized trial questions superiority of insulin pumps over injections in children

Insulin pumps and multiple daily injections deliver similar glycemic control and safety profiles when allocated alongside education and support at the point of type 1 diabetes diagnosis, say researchers.

Child with diabetes (symbolic image with model)

19-02-2019 | Ketoacidosis | Highlight | News

Data highlight opportunities to diagnose type 1 diabetes before DKA onset

Children with type 1 diabetes are more likely than their non-diabetic peers to seek primary care for a number of specific conditions in the year before their diagnosis, which could aid detection before the onset of diabetic ketoacidosis, say researchers.

Classroom

05-02-2019 | Children | Highlight | News

Children with type 1 diabetes do not suffer academically

Type 1 diabetes has no significant impact on standardized test scores in mathematics and reading for children in grades 2 to 8, show results of a study of Danish public school children.

Alarm clock and bed

14-12-2018 | Risk factors | Feature | Article

Sleep duration: Waking up to a major metabolic risk factor

The effect of sleep duration on glucose regulation and cardiometabolic risk is becoming an increasingly high-profile issue. medwireNews takes a look at the latest evidence, which shows the gravity of the problem but also offers some solutions.

Insulin pen

22-10-2018 | Mental health | Highlight | News

Insulin manipulation strongly linked to psychiatric comorbidity

Insulin manipulation, the practice of deliberately under- or overdosing insulin, is strongly associated with psychiatric comorbidity in children and young adults with type 1 diabetes, Austrian research shows.

Child with diabetes (symbolic image with model)

10-08-2018 | Cardiovascular outcomes | Highlight | News

Earlier onset of type 1 diabetes associated with increased risk for adverse outcomes

Patients with type 1 diabetes diagnosed before the age of 10 years have a higher risk for cardiovascular complications and a shorter life expectancy than those who develop the disease at an older age, study results published in The Lancet suggest.

Teenager receiving psychotherapy

01-08-2018 | Adolescents | Highlight | News

Motivational interviewing intervention fails to improve HbA1c in adolescents

The Flexible Lifestyles Empowering Change intervention has failed to improve glycated hemoglobin levels in a randomized trial involving adolescents with type 1 diabetes, despite improving some psychosocial outcomes.

Islet cells

26-06-2018 | Pathophysiology | ADA 2018 | News

RISE: Early insulin does not slow beta cell decline in youth with type 2 diabetes

The RISE trial investigators have found that increased insulin resistance and hyperresponsive beta cells may explain the rapid progression of type 2 diabetes in children.

Child hand_glucose monitor

24-06-2018 | Pediatrics | ADA 2018 | News

Parents underestimate type 1 diabetes risk in children

Many parents underestimate their child’s risk for type 1 diabetes, and although accuracy improves following a positive autoantibody result, it subsequently declines with time, a survey of TEDDY participants shows.

Teddy bear

24-06-2018 | Pathophysiology | ADA 2018 | News

TEDDY data highlight complexities of pediatric diabetes triggers

Researchers speaking at the ADA’s 78th Scientific Sessions in Orlando, Florida, USA, have presented data from The Environmental Determinants of Diabetes in the Young study that begin to shed light on genetic and environmental triggers of pediatric type 1 diabetes.

Child on iv drip

13-06-2018 | Ketoacidosis | Highlight | News

Fluid management strategy absolved of neurologic injury blame in childhood DKA

Neither the rate of administration nor the sodium chloride content of replacement fluids given to children with diabetic ketoacidosis influences their neurologic outcomes, show the results of the PECARN DKA FLUID Study.

Newborn baby

05-06-2018 | Neonatal diabetes | Highlight | News

Reassuring long-term data for sulfonylurea in neonatal diabetes

Sulfonylurea treatment is durably effective with a low rate of side effects in patients with permanent neonatal diabetes caused by mutations in the KCNJ11 gene, a study in The Lancet Diabetes & Endocrinology shows.