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Obesity

Cardiovascular disease

25-09-2023 | Gestational diabetes | News

Gestational diabetes independently linked to increased future mortality risk

Women with a history of gestational diabetes have a significantly increased risk for long-term mortality regardless of whether or not they subsequently developed type 2 diabetes.

01-12-2022 | Semaglutide | News

High-dose semaglutide reduces obesity-linked inflammatory marker

Levels of the inflammatory marker C-reactive protein decrease in people with or without type 2 diabetes taking weekly semaglutide 2.4 mg, shows analysis of three STEP trials.

Blurred image of female feet standing on weigh scales with tape measure in foreground

18-03-2022 | Cardiovascular outcomes | News

Weight gain and loss may both signal high cardiovascular risk in type 2 diabetes

The gain or loss of more than 5% bodyweight within a 2-year period is associated with an increased risk for major adverse cardiovascular events in people with type 2 diabetes, say researchers.

10-12-2021 | Heart failure | News

Study highlights importance of diabetes for obesity-related HF risk

Higher BMI, waist circumference, and fat mass are each significantly associated with an increased risk for heart failure among older people with diabetes but not among those without diabetes, US researchers report.

05-10-2021 | EASD 2021 | Conference coverage | News

Semaglutide treatment may reduce systemic inflammation

Semaglutide treatment results in significant reductions in levels of the inflammatory marker high-sensitivity C-reactive protein, indicates further analysis of the PIONEER and SUSTAIN trials.

30-09-2021 | EASD 2021 | Conference coverage | News

Insulin resistance linked to arterial stiffness in type 1 diabetes

Researchers have identified an association between insulin resistance and arterial stiffness among people with type 1 diabetes.

17-09-2021 | Metabolic surgery | News

Better cardiovascular outcomes with gastric bypass vs sleeve gastrectomy

Among people with type 2 diabetes and obesity who undergo metabolic surgery, Roux-en-Y gastric bypass is associated with a lower risk for major adverse cardiovascular events than sleeve gastrectomy, suggests a secondary analysis of a cohort study.

31-05-2021 | Hypertension | News

DiRECT analysis supports antihypertensive withdrawal before very-low-calorie diet

Blood pressure falls markedly when people with type 2 diabetes undertake a very-low-calorie diet, and immediate withdrawal of antihypertensive medications has few ill effects, say the DiRECT investigators.

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11-02-2021 | Semaglutide | At a glance | Article

A quick guide to the STEP trials

Read our round-up of the STEP phase 3 trials of semaglutide 2.4 mg in people with obesity, plus the SELECT cardiovascular outcomes trial.

12-01-2021 | Adolescents | News

Obesity flags high-risk cardiorenal profile in youth with type 1 diabetes

Adolescents with type 1 diabetes who are obese have a cardiorenal risk profile similar to that of their peers with type 2 diabetes, say researchers.

27-11-2020 | Cardiovascular disorders | News

Healthy lifestyle mitigates elevated heart disease risk in people with type 2 diabetes

People with type 2 diabetes have around a fourfold increased risk for heart disease relative to those without, but having a healthy lifestyle may lessen this risk, researchers report.

19-11-2020 | Heart failure | News

Targeting fat mass, central adiposity may reduce HF risk in type 2 diabetes

The risk for heart failure falls significantly with reductions in fat mass and waist circumference in overweight or obese people with type 2 diabetes, shows an analysis of data from the Look AHEAD trial.

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14-10-2020 | Tirzepatide | At a glance | Article

A quick guide to the SURPASS and SURMOUNT trials

Read our overview of the SURPASS trials of the dual GLP-1/GIP receptor agonist tirzepatide in people with type 2 diabetes, plus the SURMOUNT trials in people with obesity.

People in profile different age and nationalities

01-06-2020 | Risk factors | Highlight | News

Cardiometabolic burden varies by age, sex, ethnicity at type 2 diabetes diagnosis

A study shows marked variations in cardiovascular risk burden according to age, sex, and ethnicity at the point of type 2 diabetes diagnosis, with implications for both diabetes prevention and cardiovascular risk management.

13-05-2020 | Obesity | News

Genetic study backs weight loss to negate long-term childhood obesity risks

Findings from a genetic analysis support the notion that the harms of childhood obesity can be avoided by attaining a healthy BMI by adulthood.

Older couple exercising in the park

06-04-2020 | Heart failure | Highlight | News

Exercise better than diet to combat early heart changes in type 2 diabetes

The results of a small randomized trial suggest exercise is more helpful than diet for combating early cardiac dysfunction associated with type 2 diabetes, although both may be beneficial.

30-03-2020 | Older adults | News

Diabetes may compromise long-term outcomes in older people undergoing cardiac rehabilitation

Older people with and without diabetes experience similar short-term improvements in exercise capacity following cardiac rehabilitation, but those with diabetes fare worse after 1 year, EU-CaRE study results suggest.

24-03-2020 | Metabolic surgery | News

Gastric bypass benefits are wide-ranging and universally applicable in type 2 diabetes

Weight loss after gastric bypass surgery results in important cardiovascular and renal benefits for obese people with type 2 diabetes, irrespective of their baseline renal function, observational cohort study data show.

09-10-2019 | Obesity | News

Complex associations between weight regain and cardiometabolic risk

The effect of weight regain on cardiometabolic risk in people with type 2 diabetes varies according to sex, initial weight loss, and the particular risk factor under study, shows an analysis of the Look AHEAD trial.

Obesity surgery

05-09-2019 | Obesity | Highlight | News

Metabolic surgery may improve cardiovascular prognosis in type 2 diabetes

People with type 2 diabetes and obesity who undergo metabolic surgery have a significantly lower risk for major adverse cardiovascular events than those who do not receive surgery, observational study data show.