Diabetes complications and comorbidities: Ketoacidosis

A major study of children from three continents suggests that diabetic ketoacidosis remains unacceptably high among those newly identified with type 1 diabetes and shows few signs of improving.

Implementing a nursing protocol that includes point-of-care testing at triage reduces the time to diabetic ketoacidosis diagnosis and the number of unnecessary intravenous placements in the pediatric emergency department, say researchers.

Children with type 1 diabetes are more likely than their non-diabetic peers to seek primary care for a number of specific conditions in the year before their diagnosis, which could aid detection before the onset of diabetic ketoacidosis, say researchers.

Experts have developed consensus recommendations for minimizing diabetic ketoacidosis risk in patients with type 1 diabetes treated with SGLT2 inhibitors.

This 15-minute case presents likely causes of renal complications in diabetic ketoacidosis and explains how to identify the signs and symptoms of renal complications to ensure early initiation of appropriate treatment.

Get more on: Diabetic ketoacidosis | Pediatric diabetes | Nephropathy

The addition of empagliflozin to insulin therapy reduces glycated hemoglobin levels in patients with type 1 diabetes, indicate findings from the phase III EASE-2 and 3 trials.

Advisory Board member Theresa Smyth tackles an emergency case involving a type 2 diabetes patient on a new diet and treated with empagliflozin. What went wrong and how should he be managed? [Read more].

Get more on: SGLT2 inhibitors | Diet and nutritional management

Neither the rate of administration nor the sodium chloride content of replacement fluids given to children with diabetic ketoacidosis influences their neurologic outcomes, show the results of the PECARN DKA FLUID Study.

Oriot and colleagues report a case of sudden onset autoimmune type 1 diabetes with ketoacidosis in a 93-year-old woman, and summarize the available literature [read more].
Oriot P et al. Acta Diabetol 2018. doi: 10.1007/s00592-018-1170-7

Get more on: Flash glucose monitoring | Older adults | Ketoacidosis | Type 1 diabetes medication

Can you diagnose the atypical form of diabetes presented in our fourth patient case study? Test your knowledge with Editorial Board member, Jay Shubrook [read more].

Get more on: Other types of diabetes | Ketoacidosis