Diabetes complications and comorbidities

Findings from a Swedish national cohort study published in PLOS Medicine suggest that type 2 diabetes is not an important risk factor for fracture, as this risk is only “marginally” increased in people with the condition.

Higher glycated hemoglobin and the presence of kidney disease are associated with lower bone mineral density in people with type 1 diabetes, study results show.

Youth with type 2 diabetes have lower areal bone mineral density than those with obesity or who are of normal weight, according to the results of a cross-sectional study.

The quality of care among older adults with diabetes declines with increasing comorbidity and is particularly low for those with both osteoarthritis and major depression, population-based study data show.

Kohler S et al. Diabetes Care 2018: dc171525. doi: 10.2337/dc17-1525

Poor glycemic control is associated with an increased risk for low-trauma fracture in people with type 1, but not type 2, diabetes, study findings indicate.

Research based on insurance claims data indicates that new users of the sodium-glucose cotransporter-2 inhibitor canagliflozin are no more likely to experience a fracture than new users of glucagon-like peptide-1 receptor agonists.

Pieralice S et al. Curr Diab Rep 2018; 18: 84. doi: 10.1007/s11892-018-1060-y

Wilding J et al. Diabetes Ther 2018. doi: 10.1007/s13300-018-0471-8

Valentini A et al. Acta Diabetol 2018. doi: 10.1007/s00592-018-1187-y

Valderrábano RJ, Linares MI. Clin Diabetes Endocrinol 2018; 4: 9. doi: 10.1186/s40842-018-0060-9

Anagnostis P et al. Endocrine 2018; Advance online publication. doi: 10.1007/s12020-018-1548-x

DeShields SC, Cunningham TD. J Endocrinol Invest 2018; Advance online publication. doi: 10.1007/s40618-018-0828-x

Schwartz AV. Diabetologia 2017; 60: 1170–1179. doi: 10.1007/s00125-017-4283-6

Lecka-Czernik B. Diabetologia 2017; 60: 1163–1169. doi: 10.1007/s00125-017-4269-4

Ponti F et al. Endocrine 2017; 3: 426–441. doi: 10.1007/s12020-017-1278-5

Walsh JS, Vilaca T. Calcif Tissue Int 2017; 100: 528–535. doi: 10.1007/s00223-016-0229-0