medwireNews: Research from the IPD-Work consortium indicates that the mortality risk associated with work stress is largely confined to men with cardiometabolic disease.
The collaborative effort encompassed seven European cohort studies with 102,633 individuals, to shore up the “weak” evidence base for managing work stress in patients with cardiovascular disease.
It revealed that job strain was associated with significantly increased mortality among men with coronary heart disease, stroke, or diabetes, accounting for an extra 52.1 deaths per 10,000 person–years after adjustment for confounders including socioeconomic status. This effect was on a par with that of current smoking and greater than those associated with hypertension, hypercholesterolemia, obesity, physical inactivity, and high alcohol consumption.
Moreover, the effect persisted even in men who had achieved their treatment targets and followed a healthy lifestyle, Mika Kivimäki (University College London, UK) and study co-authors report in The Lancet Diabetes & Endocrinology.
Effort–reward imbalance did not influence mortality risk in men with cardiometabolic disease but increased it in men without. Neither job strain nor effort–reward imbalance affected women’s mortality risk.
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