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Pathophysiology

12-05-2022 | Pathophysiology | News

Study shows potential for type 2 diabetes characteristics to guide management

Research published in Nature Medicine shows how the specific characteristics of people with type 2 diabetes could one day guide disease management.

28-04-2022 | Tirzepatide | News

Mechanisms underlying tirzepatide efficacy revealed

Tirzepatide improves glucose control more than semaglutide in people with type 2 diabetes by improving beta-cell function as well as boosting insulin sensitivity and reducing glucagon secretion, shows a randomized trial.

26-06-2021 | ADA 2021 | Conference coverage | News

Insulin-induced hypoglycemia associated with increased cardiac workload

Hyperinsulinemic hypoglycemia is associated with an increase in left ventricular ejection fraction among people with type 1 diabetes and healthy controls, research suggests.

16-04-2021 | Pathophysiology | News

Familial, sporadic type 1 diabetes are ‘overall similar’

Children with familial type 1 diabetes have different characteristics to those with sporadic diabetes at presentation, but longer-term outcomes are similar, say researchers.

09-04-2021 | Pathophysiology | News

Ethnicity may be independently linked to beta-cell function

Black West African men have lower levels of insulin secretion in response to a meal than their White Northern European counterparts, irrespective of insulin sensitivity, study findings indicate.

09-10-2020 | Diet | News

Pancreatic morphology normalizes with sustained type 2 diabetes remission

Sustained remission of type 2 diabetes in DiRECT was accompanied by normalization of pancreatic morphology, say the researchers.

26-09-2020 | EASD 2020 | Conference coverage | News

C-peptide a reliable guide to residual beta cells across ages, diabetes durations

Levels of circulating C-peptide in people with type 1 diabetes reflect the numbers of remaining beta cells across different ages at diagnosis and durations of disease, confirm UK researchers.

24-09-2020 | EASD 2020 | Conference coverage | News

​​​​​​​‘Inappropriate’ glucagon secretions linked to postprandial glucose excursions in type 1 diabetes

Early-phase hyperglucagonemia in response to ingesting a meal is associated with postprandial glucose excursions in patients with type 1 diabetes, research suggests.