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Pathophysiology

News

09-06-2019 | Diabetes prevention | ADA 2019 | News

Teplizumab delays onset of overt type 1 diabetes

Phase II findings show that the immunotherapy teplizumab significantly prolongs the time until people at very high risk for developing type 1 diabetes are diagnosed with the condition.

09-06-2019 | Pathophysiology | ADA 2019 | News

Multiple autoantibody non-maintenance may reduce diabetes progression risk

Although a rare occurrence, non-maintenance of two or more type 1 diabetes autoantibodies may be associated with a reduced risk for progression to diabetes, show data presented at the 79th ADA Scientific Sessions in San Francisco, California, USA.

05-06-2019 | Pathophysiology | Highlight | News

Hybrid immune cell could contribute to type 1 diabetes autoimmunity

Researchers have discovered an immune cell with the attributes of both B cells and T cells, which is present in increased frequency in some people with type 1 diabetes and capable of activating insulin-specific T-helper cells.

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Opinion

04-11-2016 | Clinical trial | Editorial | Article

My EASD 2016 Highlights: From Paleolithic diets to the artificial pancreas

Editorial board member John Wilding outlines key moments from the 52nd annual meeting of the European Association for the Study of Diabetes in Munich, Germany.

In depth

14-12-2018 | Risk factors | Feature | Article

Sleep duration: Waking up to a major metabolic risk factor

The effect of sleep duration on glucose regulation and cardiometabolic risk is becoming an increasingly high-profile issue. medwireNews takes a look at the latest evidence, which shows the gravity of the problem but also offers some solutions.

Journal articles and book chapters

07-12-2018 | Pathogenesis | Review | Article

Melatonin in type 2 diabetes mellitus and obesity

Katamitri A, Jockers R. Nat Rev Endocrinol 2018. doi: 10.1038/s41574-018-0130-1

30-10-2018 | Monogenic diabetes | Review | Article

Genetics of monogenic diabetes: Present clinical challenges

Misra S, Owen KR. Curr Diab Rep 2018; 18: 141. doi: 10.1007/s11892-018-1111-4

11-10-2018 | Pathophysiology | Review | Article

The α-cell in diabetes mellitus

Gromada J, Chabosseau P, Rutter GA. Nat Rev Endocrinol 2018. doi: 10.1038/s41574-018-0097-y

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