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Medicine Matters diabetes

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Glycemic benefits of metabolic surgery endure for at least 10 years

Metabolic surgery can result in type 2 diabetes remission lasting for at least 10 years, and people who relapse still achieve markedly improved glycemic control, shows follow-up from a randomized trial published in The Lancet.

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Support for bariatric surgery in people with insulin-dependent type 2 diabetes

Treatment with bariatric surgery is associated with clinical and cost-saving benefits among obese people with type 2 diabetes requiring insulin, researchers report.

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Metformin might protect women with type 2 diabetes against COVID-19 mortality

An observational study suggests that prior metformin use may offer a protective effect against COVID-19 mortality in people with type 2 diabetes, but only for women.

EASD 2020 news

Intermittent very-low-calorie diet could be easier to stomach for people with diabetes

The pilot MIDDAS study suggests that a 2-day per week very-low-calorie diet could be a viable alternative to a continuous diet for people with type 2 diabetes who struggle with this approach.

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‘Nearly identical’ metabolic benefits with surgery vs diet in people with type 2 diabetes

Among people with obesity and type 2 diabetes, substantial weight loss is associated with similar metabolic benefits irrespective of whether it is achieved through gastric bypass surgery or diet, suggests research published in The New England Journal of Medicine.

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Type 1, type 2 diabetes linked to elevated COVID-19 mortality risk

Both type 1 and type 2 diabetes are independently associated with an increased risk for death among hospitalized patients with COVID-19, and a number of factors including poor glycemic control and BMI may predict mortality risk, suggest findings from two studies published in The Lancet Diabetes & Endocrinology.

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Ethnic-specific diabetes screening BMI cutoffs proposed

Researchers studying the MESA cohort have proposed BMI cutoffs at which people from ethnic minorities should be screened for type 2 diabetes, all of which are lower than their proposed cutoff for White people.

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Exercise better than diet to combat early heart changes in type 2 diabetes

The results of a small randomized trial suggest exercise is more helpful than diet for combating early cardiac dysfunction associated with type 2 diabetes, although both may be beneficial.

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Liraglutide 3.0 mg boosts weight loss in insulin-dependent type 2 diabetes

Adding liraglutide 3.0 mg to intensive behavioral therapy increases weight loss in overweight or obese people with insulin-treated type 2 diabetes, results of the phase 3 SCALE Insulin trial show.

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Preoperative diabetes duration may affect remission rates after bariatric surgery

Swedish research suggests that determining type 2 diabetes duration prior to bariatric surgery could help prioritize those patients most likely to achieve diabetes remission.

25-09-2023 | Gestational diabetes | News

Gestational diabetes independently linked to increased future mortality risk

Women with a history of gestational diabetes have a significantly increased risk for long-term mortality regardless of whether or not they subsequently developed type 2 diabetes.

15-09-2023 | Type 2 diabetes | News

Young-onset type 2 diabetes diagnosis linked to shortened life expectancy

Younger age at type 2 diabetes diagnosis is associated with shorter life expectancy, with 3 to 4 years lost for every decade of earlier diagnosis.

Gastric bypass surgery (used with permission)

28-07-2023 | Type 2 diabetes | News

Better QoL after gastric bypass than sleeve gastrectomy for people with type 2 diabetes

Patients undergoing gastric bypass experience superior patient-reported outcomes, diabetes remission rates and weight loss compared with sleeve gastrectomy.

14-07-2023 | Type 2 diabetes | News

Cagrilintide plus semaglutide shows dual benefit in type 2 diabetes

Improved glycemic control and weight loss seen with the coadministration of cagrilintide and semaglutide in a phase 2 trial.

Doctor measures a man's waist

03-07-2023 | Type 2 diabetes | News

‘Substantial’ bodyweight reductions with tirzepatide in people with type 2 diabetes and obesity

SURMOUNT-2 trial results show bodyweight reductions with tirzepatide that rival those seen with other approved anti-obesity medications in people with type 2 diabetes.

05-06-2023 | Prediabetes | News

Caloric restriction outperforms liraglutide for weight loss in prediabetes

Using liraglutide in people with obesity and prediabetes is a valuable strategy for weight loss, but improvements are greater with caloric restriction alone, suggest study results.

04-05-2023 | Diet | News

DiRECT extension shows potential for persistent type 2 diabetes remission

The 5-year DiRECT results show sustained type 2 diabetes remission for 13% of the intervention group.

25-04-2023 | Diet | News

Time-restricted fasting improves postprandial glucose tolerance

Restricting fast-day eating to the morning has a positive effect on postprandial glucose versus standard calorie restriction among people at increased risk for type 2 diabetes who are trying to lose weight, a study shows.

Tape measure - overweight obesity concept

14-02-2023 | Obesity | News

Obesity as prevalent in type 1 diabetes as general US population

There is a “substantial” burden of overweight and obesity among people with type 1 diabetes, say US researchers who found rates to be in line with that of the general population.

09-01-2023 | Semaglutide | News

FDA approves high-dose semaglutide for adolescents with obesity

Read more about this decision here

19-12-2022 | Early onset | News

Global type 2 diabetes burden increasing in adolescents and young adults

The incidence and burden of type 2 diabetes in young people aged 15–39 years are increasing worldwide, show data from the Global Burden of Disease Study.

16-12-2022 | Diet | News

Intermittent fasting feasible with insulin-treated type 2 diabetes

A randomized trial reveals benefits of intermittent fasting, without an increased risk for severe hypoglycemia, in people with insulin-treated type 2 diabetes.

13-12-2022 | Diet | News

Low-carb, high-fat diet gives glycemic benefits in randomized trial

Randomized trial findings show reduced glycated hemoglobin and bodyweight in people with type 2 diabetes following a calorie-unrestricted low-carbohydrate, high-fat diet versus a high-carbohydrate, low-fat approach.

01-12-2022 | Semaglutide | News

High-dose semaglutide reduces obesity-linked inflammatory marker

Levels of the inflammatory marker C-reactive protein decrease in people with or without type 2 diabetes taking weekly semaglutide 2.4 mg, shows analysis of three STEP trials.