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Medicine Matters diabetes

Featured clinical trials

18-09-2017 | PCSK9 inhibitors | EASD 2017 | News

FOURIER: Evolocumab cardiovascular benefits extend to diabetes patients

A prespecified analysis of the FOURIER trial shows that the PCSK9 inhibitor evolocumab is as beneficial in patients with diabetes as in those without.

18-09-2017 | Glycemic control | EASD 2017 | News

J-DOIT3 supports intensive management to prevent diabetic complications

The J-DIOT3 trial results support the findings from Steno-2, showing that intensive risk factor management can reduce the risk for complications in patients with type 2 diabetes.

15-09-2017 | Hypoglycemia | EASD 2017 | News

Glycemic variability, hypoglycemia linked to poor outcomes in type 2 diabetes patients

Two secondary analyses of the DEVOTE trial suggest that type 2 diabetes patients with high day-to-day fasting glycemic variability and those who experience severe hypoglycemia are at increased risk for adverse outcomes.

15-09-2017 | Continuous glucose monitoring | EASD 2017 | News

CGM use during pregnancy improves maternal glycemic control, neonatal outcomes

The CONCEPTT trial results suggest that the use of continuous glucose monitoring by pregnant women with type 1 diabetes improves glycemic control and neonatal outcomes relative to standard glucose monitoring.

15-09-2017 | Exenatide | EASD 2017 | News

EXSCEL: Near miss for exenatide cardioprotection

The results of the Exenatide Study of Cardiovascular Event Lowering study show that the glucagon-like peptide-1 receptor agonist has a neutral cardiovascular effect, the investigators have reported at the EASD annual meeting, in Lisbon, Portugal.

14-09-2017 | Dapagliflozin | EASD 2017 | News

DEPICT-1 findings support dapagliflozin as add-on therapy for type 1 diabetes

Dapagliflozin is a promising adjunct treatment to insulin for patients with type 1 diabetes, suggest phase III trial results presented at the EASD annual meeting in Lisbon, Portugal, and published simultaneously in The Lancet Diabetes & Endocrinology.

14-09-2017 | Type 1 diabetes | EASD 2017 | News

Add-on sotagliflozin improves glycemic control in type 1 diabetes patients

Results of the inTandem3 study suggest that adding the sodium–glucose cotransporter 1 and 2 inhibitor sotagliflozin to insulin treatment improves glycemic control among patients with type 1 diabetes, but at the cost of an increased risk for ketoacidosis.

13-09-2017 | Acarbose | EASD 2017 | News

ACE results suggest no reduction in CV risk with acarbose treatment

The α-glucosidase inhibitor acarbose does not reduce cardiovascular risk but could decrease the risk for developing type 2 diabetes among patients with coronary heart disease and impaired glucose tolerance, results of the phase IV placebo-controlled ACE trial suggest.

13-09-2017 | Pioglitazone | EASD 2017 | News

TOSCA.IT: Similar long-term CV safety profile for pioglitazone, sulfonylurea

 The TOCSA.IT investigators have found no differences in cardiovascular disease outcomes between patients with type 2 diabetes taking pioglitazone versus sulfonylurea over nearly 5 years.

Expert commentaries

Research news: Diabetes medications

22-09-2017 | Older adults | EASD 2017 | News

Optimizing outcomes: System and patient factors

An EASD session on optimizing patient outcomes included research into the effect of guideline adherence, predictors of changes in medication adherence, and overtreatment of older people with diabetes.

22-09-2017 | Insulin glargine | EASD 2017 | News

Higher dose of insulin glargine supported for type 2 diabetes

Results of a pooled analysis suggest that the 300 U/mL dose of insulin glargine is associated with a lower risk for hypoglycemia than the 100 U/mL dose.

21-09-2017 | Type 2 diabetes | EASD 2017 | News

Novel compounds show promise for type 2 diabetes

Study results presented at the EASD annual meeting in Lisbon, Portugal, demonstrated the potential of several novel therapies for the treatment of obesity-related metabolic dysfunction and type 2 diabetes.

20-09-2017 | Hypoglycemia | EASD 2017 | News

Hypoglycemia: Risk factors and Ramadan

Results presented during an EASD annual meeting session on hypoglycemia covered risk factors and consequences, and looked at the optimal insulin management approach for diabetes patients wishing to observe Ramadan.

20-09-2017 | Non-alcoholic fatty liver disease | EASD 2017 | News

NAFLD: The associated risks and potential treatments

Researchers presented the results of several studies investigating the risks associated with nonalcoholic fatty liver disease and potential treatment strategies at the EASD annual meeting in Lisbon, Portugal.

19-09-2017 | Sotagliflozin | EASD 2017 | News

Sotagliflozin as adjunct therapy to insulin ‘might be a treatment option’ for type 1 diabetes

Sotagliflozin may be an effective add-on therapy to insulin for patients with type 1 diabetes, but the benefits are less clear in a young adult population, suggest the results of two studies presented at the EASD annual meeting in Lisbon, Portugal.

19-09-2017 | Empagliflozin | EASD 2017 | News

Benefits of empagliflozin unlikely to be mediated by control of cardiovascular risk factors

Analysis of data from the EMPA-REG OUTCOME trial suggests that the beneficial effects of empagliflozin on mortality risk in patients with type 2 diabetes and established cardiovascular disease occur independently of its influence on traditional cardiovascular risk factors.

18-09-2017 | PCSK9 inhibitors | EASD 2017 | News

FOURIER: Evolocumab cardiovascular benefits extend to diabetes patients

A prespecified analysis of the FOURIER trial shows that the PCSK9 inhibitor evolocumab is as beneficial in patients with diabetes as in those without.

15-09-2017 | Hypoglycemia | EASD 2017 | News

Glycemic variability, hypoglycemia linked to poor outcomes in type 2 diabetes patients

Two secondary analyses of the DEVOTE trial suggest that type 2 diabetes patients with high day-to-day fasting glycemic variability and those who experience severe hypoglycemia are at increased risk for adverse outcomes.

Research news: Diabetic complications

22-09-2017 | Older adults | EASD 2017 | News

Optimizing outcomes: System and patient factors

An EASD session on optimizing patient outcomes included research into the effect of guideline adherence, predictors of changes in medication adherence, and overtreatment of older people with diabetes.

22-09-2017 | Insulin glargine | EASD 2017 | News

Higher dose of insulin glargine supported for type 2 diabetes

Results of a pooled analysis suggest that the 300 U/mL dose of insulin glargine is associated with a lower risk for hypoglycemia than the 100 U/mL dose.

20-09-2017 | Hypoglycemia | EASD 2017 | News

Hypoglycemia: Risk factors and Ramadan

Results presented during an EASD annual meeting session on hypoglycemia covered risk factors and consequences, and looked at the optimal insulin management approach for diabetes patients wishing to observe Ramadan.

20-09-2017 | Non-alcoholic fatty liver disease | EASD 2017 | News

NAFLD: The associated risks and potential treatments

Researchers presented the results of several studies investigating the risks associated with nonalcoholic fatty liver disease and potential treatment strategies at the EASD annual meeting in Lisbon, Portugal.

19-09-2017 | Sotagliflozin | EASD 2017 | News

Sotagliflozin as adjunct therapy to insulin ‘might be a treatment option’ for type 1 diabetes

Sotagliflozin may be an effective add-on therapy to insulin for patients with type 1 diabetes, but the benefits are less clear in a young adult population, suggest the results of two studies presented at the EASD annual meeting in Lisbon, Portugal.

19-09-2017 | Diabetes distress | EASD 2017 | News

Identifying diabetes distress may help direct healthcare resources

Researchers find that routinely asking patients with type 1 diabetes to complete the Diabetes Distress Scale-2 may direct more healthcare resources to those who need them and help to improve outcomes.

19-09-2017 | Cardiovascular outcomes | EASD 2017 | News

Simple wellbeing query predicts MACE in type 2 diabetes

Asking two simple questions about the vitality and energy of patients with type 2 diabetes may help healthcare providers to predict their risk for major adverse cardiovascular events.

18-09-2017 | Glycemic control | EASD 2017 | News

J-DOIT3 supports intensive management to prevent diabetic complications

The J-DIOT3 trial results support the findings from Steno-2, showing that intensive risk factor management can reduce the risk for complications in patients with type 2 diabetes.

15-09-2017 | Hypoglycemia | EASD 2017 | News

Glycemic variability, hypoglycemia linked to poor outcomes in type 2 diabetes patients

Two secondary analyses of the DEVOTE trial suggest that type 2 diabetes patients with high day-to-day fasting glycemic variability and those who experience severe hypoglycemia are at increased risk for adverse outcomes.

Other research news

22-09-2017 | Older adults | EASD 2017 | News

Optimizing outcomes: System and patient factors

An EASD session on optimizing patient outcomes included research into the effect of guideline adherence, predictors of changes in medication adherence, and overtreatment of older people with diabetes.

19-09-2017 | Genetics | EASD 2017 | News

Genetics point way to type 1 and monogenic diagnosis and prediction

Studies presented in a session on the genetics of diabetes, at the EASD annual meeting in Lisbon, Portugal, demonstrated the heterogeneity of type 1 diabetes risk and the predictive and diagnostic power of a genetic risk score.

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