Diabetes complications and comorbidities: Hyperglycemia

Glycated hemoglobin levels correlate strongly with continuous glucose monitoring-measured average blood glucose and hyperglycemia, but poorly with hypoglycemia, say researchers.

Researchers report that having type 1 diabetes may affect children’s brain growth and cognitive development, with persistent hyperglycemia the most likely culprit.

A large proportion of mobile apps for self-management of blood glucose do not provide real-time decision support for users with type 2 diabetes, researchers report.

Flash glucose monitoring significantly reduces time in hyperglycemia or hypoglycemia in people with diabetes at high risk for either outcome, with the benefit sustained for at least 6 months, real-world study data show.

Researchers show that closed-loop insulin delivery achieves markedly better glucose control than standard insulin management in hospitalized patients with hyperglycemia receiving enteral or parenteral nutrition.

The final version of the 2018 update to the consensus guidelines on managing hyperglycemia in people with type 2 diabetes is now published.

A large proportion of people with documented hyperglycemia are still not clinically diagnosed with type 2 diabetes for up to 1 year later, US study data show.

An analysis of the UK Clinical Practice Research Datalink indicates that elevated glycated hemoglobin levels are associated with an increased risk for infection among patients with diabetes.

Young patients with type 1 diabetes who have inadequate access to nutritional food are more likely to have poor glycemic control than those from food-secure households, researchers report.

Research shows that intervening to improve the diet quality of adolescents with type 1 diabetes does not exacerbate disordered eating behavior.

A bidirectional relationship between depression and severe dysglycemia exists among older people with type 1 diabetes, indicating a need for increased vigilance in this population.

Analysis of gene expression changes underlying excess glucose production in the liver has identified a drug – derived from broccoli – with a mechanism of action complementary to that of metformin.

Patients with type 2 diabetes who experience a large reduction in glycated hemoglobin levels within 6 months of starting metformin therapy have a lower risk for adverse outcomes than those who do not achieve early glycemic control, study results suggest.

Research suggests that a predictive low-glucose management system significantly reduces hypoglycemic events in children and adolescents with type 1 diabetes.

Results of the Onset 1 trial confirm that treatment with fast-acting insulin aspart provides improves glycemic control compared with conventional insulin aspart among adults with type 1 diabetes.

Research shows that switching to an insulin pump does not improve glycemic control in patients referred to an educational program after struggling to control their type 1 diabetes with multiple daily injections.

A study suggests that use of a virtual glucose management service can reduce hyper- and hypoglycemia among inpatients with diabetes by around a third.

Results of a randomized trial suggest that continuous glucose monitoring can be used without regular confirmatory blood glucose monitoring among adult insulin pump users with well-controlled type 1 diabetes.

Elevated blood glucose within the normal range is associated with increasing arterial stiffness over the long term in participants of the Whitehall II study.

Having a physician who speaks their native language is associated with improved glycemic control among diabetes patients with limited English proficiency, but may be less important for medication adherence, research suggests.