02-26-2018 | Complications | Figure | Image
Impact of diabetic complications
Diabetes mellitus is the leading cause of new blindness in working-age people and the leading cause of end-stage renal disease. More than 60% of diabetic patients are affected by neuropathy, which includes distal symmetrical polyneuropathy, mononeuropathies, and a variety of autonomic neuropathies that cause erectile dysfunction, urinary incontinence, gastroparesis, and nocturnal diarrhea. Diabetic neuropathy, in conjunction with accelerated lower extremity arterial disease, accounts for more than 50% of all non-traumatic amputations in the USA. Diabetes and impaired glucose tolerance increase cardiovascular disease risk three to eightfold.