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Cardiovascular disease

Cardiovascular disease

Human heart with ecg graph. 3d illustration

11-18-2022 | Dapagliflozin | News

Dapagliflozin HFpEF benefits independent of glucose levels

People who have heart failure with preserved ejection fraction benefit from dapagliflozin irrespective of whether they have normal or impaired glucose metabolism, shows further analysis of DELIVER.

06-01-2022 | Cardiovascular outcomes | News

No long-term CV benefits seen 2 decades after DPP interventions

People with impaired glucose tolerance who received metformin or intensive lifestyle intervention during the DPP trial show no sign of a significantly reduced cardiovascular disease risk 21 years later, reveal the latest DPPOS results.

04-14-2022 | Prediabetes | News

Retinal microvascular damage evident before type 2 diabetes diagnosis

People with hypertension and prediabetes have significantly lower capillary density in the foveal retinal region, indicating microvascular damage, than those with hypertension but normal glucose metabolism, say researchers.

10-27-2021 | Prediabetes | News

Cardiovascular risk greatest among people with prediabetes

People with glycated hemoglobin levels just below the diabetes diagnosis threshold have the greatest risk for major adverse cardiovascular events and death, suggests a study of individuals in the upper normal glycemic range.

Artery illustration

06-11-2021 | Glycemic control | News

Daily glycemic variability may contribute to aortic stiffness

Higher daily glucose variability is associated with greater aortic stiffness irrespective of average glucose levels, indicate findings from The Maastricht Study.

HbA1c test and atherosclerosis concept

06-01-2021 | Atherosclerosis | News

Prediabetic, high normal HbA1c levels linked to subclinical atherosclerosis risk

The risk for subclinical atherosclerosis among people at low risk for cardiovascular death increases with increasing glycated hemoglobin levels and is raised even at levels below the prediabetes threshold, research shows.

05-16-2021 | Prediabetes | Conference coverage | News

‘Substantial gradient’ of cardiorenal risk at prediabetic glucose levels

The risk for adverse cardiorenal events begins to increase well below the glycemic level associated with type 2 diabetes, with the largest proportion of events occurring in people with prediabetic levels, shows a UK Biobank analysis.

03-09-2021 | Cardiovascular outcomes | News

Casual glucose level linked to CVD risk in absence of diabetes

A random blood glucose test in people without diabetes may provide a good indication of who has an increased risk for developing cardiovascular disease over the subsequent decade, a study suggests.

11-17-2020 | Empagliflozin | News

Favorable LV remodeling may contribute to empagliflozin benefits

The SGLT2 inhibitor empagliflozin may reverse adverse left ventricular remodeling in people who have heart failure with reduced ejection fraction and type 2 diabetes or prediabetes, shows a randomized trial.

07-21-2020 | Cardiovascular outcomes | News

Sex differences in MI risk in type 2 diabetes explored

The excess risk for myocardial infarction associated with having diabetes may be greater in women than men, despite men having a higher frequency of events overall, shows research from the UK Biobank.

07-17-2020 | Prediabetes | News

Updated meta-analysis confirms prediabetes link with mortality, CVD risk

Prediabetes is associated with an elevated risk for all-cause mortality and cardiovascular events, both in the general population and in patients with atherosclerotic cardiovascular disease, shows an updated meta-analysis published in The BMJ.

Tablet device showing the chemical structure of Metformin

06-16-2020 | ADA 2020 | Conference coverage | News

DPPOS: No change to cancer risk with long-term metformin use

Among the latest findings from the DPP Outcomes Study is that long-term use of metformin does not affect the risk for cancer.

People in profile different age and nationalities

06-01-2020 | Risk factors | Highlight | News

Cardiometabolic burden varies by age, sex, ethnicity at type 2 diabetes diagnosis

A study shows marked variations in cardiovascular risk burden according to age, sex, and ethnicity at the point of type 2 diabetes diagnosis, with implications for both diabetes prevention and cardiovascular risk management.

Cartoon of overweight man walking on a 'cardiovascular tightrope'

05-05-2020 | Prediabetes | Highlight | News

Prediabetes marks increased vascular risk

People who meet the criteria for prediabetes during the 3 years before a type 2 diabetes diagnosis have a higher burden of vascular disease than those who do not, research shows.

05-02-2019 | Cardiovascular disorders | News

Metformin may be cardioprotective in patients with coronary artery disease

Findings from the MET-REMODEL trial suggest that metformin treatment may aid regression of left ventricular hypertrophy among nondiabetic patients with coronary artery disease.

04-26-2019 | Diabetes prevention | News

Da Qing study: Lifestyle intervention benefits persist for decades

Lifestyle interventions to delay the onset of type 2 diabetes result in marked long-term reductions in cardiovascular disease and mortality, shows the 30-year follow-up of the Da Qing Diabetes Prevention Outcome Study.

11-28-2018 | Diabetic cardiomyopathy | Article

Cardiovascular risk reduction over time in patients with diabetes or pre-diabetes undergoing bariatric surgery: data from a single-center retrospective observational study

Rubio-Almanza M, Cámara-Gómez R, Hervás-Marín D et al. BMC Endocr Disord 2018; 18: 90. doi: 10.1186/s12902-018-0317-4

06-24-2018 | Lifestyle interventions | ADA 2018 | News

Lifestyle intervention cuts long-term CVD events in people at risk for diabetes

A 6-year diet and exercise intervention significantly reduces the long-term risk for cardiovascular disease in Chinese adults with impaired glucose tolerance, research suggests.

06-22-2018 | Monogenic diabetes | Review | Article

Advances in the genetics of youth-onset type 2 diabetes

Todd JN, Srinivasan S, Pollin TI. Curr Diab Rep 2018; 18: 57. doi: 10.1007/s11892-018-1025-1

06-06-2018 | Mental health | Article

The relationship between sleep and cognitive function in patients with prediabetes and type 2 diabetes

Saetung S et al. Acta Diabetol 2018. doi: 10.1007/s00592-018-1166-3