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Pathophysiology

News

12-18-2018 | Pathophysiology | News

Pancreatic volume reductions occur early in diabetes disease process

Individuals with recently diagnosed type 1 diabetes, as well as their first-degree relatives, have significantly smaller pancreases than individuals with no history of diabetes, show two studies published in Diabetes Care.

10-09-2018 | Children | EASD 2018 | News

RISE pediatric findings consistent over longer term

The RISE investigators have reported a continued lack of effect of early intensive therapy on beta-cell function decline in children with prediabetes or early type 2 diabetes.

07-13-2018 | Pathophysiology | News

Ethnicity, BMI modify risk for progression toward type 1 diabetes

Findings from the Type 1 Diabetes TrialNet Study Group show both independent and interacting effects of ethnicity, age, and BMI on progression toward type 1 diabetes in at-risk people.

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Opinion

11-04-2016 | Clinical trial | Editorial | Article

My EASD 2016 Highlights: From Paleolithic diets to the artificial pancreas

Editorial board member John Wilding outlines key moments from the 52nd annual meeting of the European Association for the Study of Diabetes in Munich, Germany.

In depth

12-14-2018 | Risk factors | Feature | Article

Sleep duration: Waking up to a major metabolic risk factor

The effect of sleep duration on glucose regulation and cardiometabolic risk is becoming an increasingly high-profile issue. medwireNews takes a look at the latest evidence, which shows the gravity of the problem but also offers some solutions.

Journal articles and book chapters

12-07-2018 | Pathogenesis | Review | Article

Melatonin in type 2 diabetes mellitus and obesity

Katamitri A, Jockers R. Nat Rev Endocrinol 2018. doi: 10.1038/s41574-018-0130-1

10-30-2018 | Monogenic diabetes | Review | Article

Genetics of monogenic diabetes: Present clinical challenges

Misra S, Owen KR. Curr Diab Rep 2018; 18: 141. doi: 10.1007/s11892-018-1111-4

10-11-2018 | Pathophysiology | Review | Article

The α-cell in diabetes mellitus

Gromada J, Chabosseau P, Rutter GA. Nat Rev Endocrinol 2018. doi: 10.1038/s41574-018-0097-y

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