Islet autoantibody negativity plus mild hyperglycemia and a family history of diabetes can be used to identify children newly diagnosed with diabetes who should undergo genetic testing for maturity-onset diabetes of the young, study findings indicate.
Allocating people with diabetes to one of five previously described data-driven clusters may help to identify those at high immediate risk for developing diabetic neuropathy or non-alcoholic fatty liver disease, say researchers.
Baseline glucose control, diabetes duration, and BMI all impact whether an individual achieves optimal glucose control after a genetic diagnosis and treatment change for maturity onset diabetes of the young, UK researchers report.
Only a very small proportion of adolescents and young adults with diabetes who are referred for outpatient psychotherapy actually receive these services, even when there is an integrated pediatric psychologist in the clinic, research shows.
Sulfonylurea treatment is durably effective with a low rate of side effects in patients with permanent neonatal diabetes caused by mutations in the KCNJ11 gene, a study in The Lancet Diabetes & Endocrinology shows.
Studies presented in a session on the genetics of diabetes, at the EASD annual meeting in Lisbon, Portugal, demonstrated the heterogeneity of type 1 diabetes risk and the predictive and diagnostic power of a genetic risk score.
Researchers report two cases of children with severe and irreversible neurologic damage caused by complications at the time of neonatal diabetes diagnosis, highlighting the need for increased awareness of the condition.
Genetic analysis of children in a national registry reveals undiagnosed maturity-onset diabetes of the young among antibody-negative patients with type 1 diabetes, with implications for their treatment.