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Monogenic diabetes


09-24-2020 | EASD 2020 | Conference coverage | News

GLIMLINA: Glimepiride–linagliptin combination shows potential for HNF1A-MODY

Adding linagliptin to glimepiride treatment reduces some measures of glycemic variability and improves glycemic control in patients with HNF1A-MODY, indicate findings from the GLIMLINA trial.

11-14-2019 | MODY | News

Islet autoantibody negativity, mild hyperglycemia should trigger MODY genetic screening

Islet autoantibody negativity plus mild hyperglycemia and a family history of diabetes can be used to identify children newly diagnosed with diabetes who should undergo genetic testing for maturity-onset diabetes of the young, study findings indicate.

07-29-2019 | Pathophysiology | News

Cluster analysis may help to predict diabetic complications

Allocating people with diabetes to one of five previously described data-driven clusters may help to identify those at high immediate risk for developing diabetic neuropathy or non-alcoholic fatty liver disease, say researchers.

06-08-2019 | Monogenic diabetes | ADA 2019 | News

Monogenic diabetes mutations prevalent in type 2 diabetes

People with type 2 diabetes have a high prevalence of pathogenic mutations in genes typically associated with monogenic diabetes.

03-07-2019 | Diagnosis | DUKPC 2019 | News

Double-checking C-peptide well after type 1 diagnosis can lead to reclassifications

Measuring C-peptide in everyone a minimum of 3 years after a clinical diagnosis of type 1 diabetes can result in some people being reclassified with other forms of diabetes, researchers report.

09-26-2018 | Monogenic diabetes | News

Clinical factors predict good glycemic control after MODY treatment switch

Baseline glucose control, diabetes duration, and BMI all impact whether an individual achieves optimal glucose control after a genetic diagnosis and treatment change for maturity onset diabetes of the young, UK researchers report.

06-24-2018 | Adolescents | ADA 2018 | News

Adolescents with diabetes often not getting the psychotherapy services they need

Only a very small proportion of adolescents and young adults with diabetes who are referred for outpatient psychotherapy actually receive these services, even when there is an integrated pediatric psychologist in the clinic, research shows.

06-05-2018 | Neonatal diabetes | Highlight | News

Reassuring long-term data for sulfonylurea in neonatal diabetes

Sulfonylurea treatment is durably effective with a low rate of side effects in patients with permanent neonatal diabetes caused by mutations in the KCNJ11 gene, a study in The Lancet Diabetes & Endocrinology shows.

09-19-2017 | Genetics | EASD 2017 | News

Genetics point way to type 1 and monogenic diagnosis and prediction

Studies presented in a session on the genetics of diabetes, at the EASD annual meeting in Lisbon, Portugal, demonstrated the heterogeneity of type 1 diabetes risk and the predictive and diagnostic power of a genetic risk score.

08-22-2017 | Neonatal diabetes | News

Dried blood spot screening shows promise for neonatal diabetes

Neonatal diabetes could be detected as early as day 5 of life using glucose measurements from dried blood spots, researchers report.

08-02-2017 | Monogenic diabetes | News

A new biomarker screening pathway for diagnosing monogenic diabetes

Researchers have developed a new biomarker screening pathway to systematically screen all patients with young-onset diabetes for monogenic diabetes.

02-09-2017 | Ketoacidosis | News

Neonatal diabetes complications can have profound impact

Researchers report two cases of children with severe and irreversible neurologic damage caused by complications at the time of neonatal diabetes diagnosis, highlighting the need for increased awareness of the condition.

12-07-2016 | MODY | News

Antibody-negative type 1 diabetes may be undiagnosed MODY

Genetic analysis of children in a national registry reveals undiagnosed maturity-onset diabetes of the young among antibody-negative patients with type 1 diabetes, with implications for their treatment.

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