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Type 2 diabetes


12-14-2017 | Empagliflozin | News

Plasma volume reduction may explain much of empagliflozin cardioprotective effect

A mediation analysis indicates that empagliflozin may provide cardioprotection largely through its ability to reduce plasma volume, with traditional cardiovascular risk markers playing little or no role.

12-13-2017 | Cardiovascular outcomes | News

Prognostic value of UACR depends on availability of cardiac biomarkers

An increased urinary albumin to creatinine ratio is significantly and independently associated with an increased risk for cardiovascular outcomes in patients with type 2 diabetes, an analysis of SAVOR-TIMI 53 data shows.

12-12-2017 | Anti-hypertensive medications | News

Intensive BP treatment back on table for diabetes patients

Intensive blood pressure management benefits patients whether or not they have diabetes and regardless of their baseline level of cardiovascular disease risk, shows a pooled analysis of the SPRINT and ACCORD-BP trials.

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12-14-2017 | Guidelines | Editorial | Article

What is new in the 2018 American Diabetes Association Standards of Medical Care in Diabetes?

Jay Shubrook, Chair of the American Diabetes Association’s Primary Care Advisory Group, outlines what's new in 2018's ADA Standards of Care update. 

11-28-2017 | Type 2 diabetes | Editorial | Article

Real-world evidence: Complementing clinical trials in type 2 diabetes

Editorial Board member John Wilding examines what real-world data means to today’s clinicians and presents his vision for the future of this type of evidence.

11-13-2017 | Specific populations | Interview | Video

Women and diabetes - our right to a healthy future

Editorial Board member Lori Berard addresses 2017's World Diabetes Day theme, providing her insights on the key considerations for managing diabetes in women in this interview with Medicine Matters diabetes.

In depth

10-17-2017 | Glucagon-like peptide-1 agonists | Feature | Article

GLP-1 receptor agonists: Cardiovascular trials and triumphs

With four GLP-1 receptor agonists now having published cardiovascular outcome data, medwireNews takes a look at how the experts are interpreting the conflicting findings, and what they mean for prescribing decisions.

08-22-2017 | Canagliflozin | Podcast | Audio

Dissecting the CANVAS trial

Listen to editorial board members and CANVAS investigators Carol Wysham and Lori Berard discussing the efficacy and safety findings of the trials.

Original research

01-19-2017 | Pregnancy | OriginalPaper | Article

Translating HbA1c measurements into estimated average glucose values in pregnant women with diabetes

The HbA1c–average glucose relationship is altered by pregnancy. Routinely generated standard estimated average glucose values do not account for this difference between pregnant and non-pregnant individuals and, thus, should not be used during pregnancy. Instead, the pregnancy-specific estimated average glucose values deduced in the current study are recommended for antenatal clinical care.

Law GR et al. Diabetologia 2017;60:618–624. doi:10.1007/s00125-017-4205-7

Related news story: Pregnancy-specific glucose to HbA1c conversion is essential

11-01-2016 | Type 2 diabetes | OriginalPaper | Article

Implications of the EMPA-REG Trial for Clinical Care and Research

An expert review of the EMPA-REG trial’s main findings, mechanisms that could explain its results, suggestions for ways in which clinical care may be influenced, and directions for future research.

Stamatouli AM & Inzucchi SE. Curr Diab Rep 2016;16:131. doi:10.1007/s11892-016-0822-7

Journal articles and book chapters

11-02-2017 | Cardiovascular disorders | Review | Article

Treating disease mechanisms in patients with heart failure and diabetes mellitus

We explore mechanisms that may serve as potential treatment targets and review the effects of various contemporary glucose-lowering agents on heart failure outcomes.

Trang A, Aguilar D. Curr Heart Fail Rep 2017;14:445–453. doi:10.1007/s11897-017-0371-7

10-27-2017 | Type 1 diabetes | Review | Article

Diabetes and the pancreatobiliary diseases

The authors present an updated and concise review of the association between diabetes and common disorders of the pancreaticobiliary system, including pancreatitis, pancreatic cancer, and biliary dyskinesia.

Shafqet M, Sharzehi K. Curr Treat Options Gastro 2017;15:508–519. doi:10.1007/s11938-017-0163-x

10-23-2017 | Cardiovascular disorders | Review | Article

Translating recent results from the Cardiovascular Outcomes Trials into clinical practice: Recommendations from the Central and Eastern European Diabetes Expert Group (CEEDEG)

The authors develop regional expert consensus recommendations with aim of improving the care of patients with type 2 diabetes at high cardiovascular risk in Central and Eastern Europe.

Schernthaner G et al. Cardiovasc Diabetol 2017;16:137. doi:10.1186/s12933-017-0622-7

In practice

06-01-2017 | Type 2 diabetes | Review | Article

Practical recommendations for transitioning patients with type 2 diabetes from hospital to home

This review provides clinicians with practical evidence-based recommendations for transitioning hospitalized patients with type 2 diabetes to home.

Donihi AC. Curr Diab Rep 2017; 17: 52. doi:10.1007/s11892-017-0876-1

05-08-2017 | Type 1 diabetes | Review | Article

A practical review of C-Peptide testing in diabetes

Leighton et al. offer a rationale for the practical and pragmatic use of c-peptide testing to guide the clinical management of individuals with diabetes.

Leighton E, Sainsbury CA, & Jones GC. Diabetes Ther 2017; 8: 475–487. doi:10.1007/s13300-017-0265-4

04-04-2017 | Screening | Article

Understanding type 2 diabetes mellitus screening practices among primary care physicians: A qualitative chart-stimulated recall study

Hafez et al. scrutinized the screening practices of primary care physicians and found that previous screening test results, visit types, and patients’ weight and age influenced their decisions to screen for type 2 diabetes.

Hafez D et al. BMC Fam Pract 2017;18:50. doi:10.1186/s12875-017-0623-3

Case reports

12-13-2017 | Diagnosis | Case report | Article

Atypical diabetes: Case 3

How would you diagnose and treat the third patient in our case series on atypical forms of diabetes? Editorial board member Jay Shubrook challenges you.

Jay Shubrook DO

01-01-2015 | Type 2 diabetes | Case report | Article

T2DM diagnosis and evaluation

What are the relevant diagnostic criteria, recommended evaluations, and appropriate glycemic goals for the new patient with T2DM?

Miller JD. In: A Case-Based Guide to Clinical Endocrinology. Edited by Davies TF. Springer New York, 2015.

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